Protection of cancer

Throughout the 1970s, studies by Cameron, Campbell, and Pauling optional that high-dose vitamin C has useful property on quality of life and endurance time in patients with terminal cancer .However, some ensuing studies—including a randomized, double-blind, placebo-controlled clinical trial by Mortal and colleagues at the Mayo Clinic did not bear these findings. In the Mortal study, patients with advanced correctional cancer who received 10 g/day vitamin C fared no better than those getting a placebo. The authors of a 2003 review assessing the effects of vitamin C in patients with superior cancer completed that vitamin C confers no significant mortality benefit Emerging study suggests that the route of vitamin C administration (intravenous vs. oral) could make clear the conflicting findings Most intervention trials, including the one conducted by Mortal and colleagues, used only oral direction, whereas Cameron and colleagues used a combination of oral and intravenous (IV) administration. Oral administration of vitamin C, even of very large doses, can raise plasma vitamin C concentrations to a most of only 220 micro mole/L, whereas IV administration can make plasma concentration as high as 26,000 micro mole/L Concentrations of this magnitude are selectively toxicity to tumor cells in vitriol .Research in mice suggests that pharmacological doses of IV vitamin C might show promise in treating otherwise difficult-to-treat tumors .A high attention of vitamin C may act as a pro-oxidant and generate hydrogen peroxide that has selective toxicity toward cancer cells .Based on these findings and a few case reports of patients with advanced cancers who had remarkably long endurance times following administration of high-dose IV vitamin C, some researchers support reassessment of the use of high-dose IV vitamin C as a drug to treat cancer .As discussed below, it is uncertain whether supplemental vitamin C and other antioxidants might interact with chemotherapy and/or energy .Therefore, individuals undergoing these actions should consult with their oncologist prior to taking vitamin C or other antioxidant supplements, particularly in high doses .